Steroids and Autism: What Large Cohorts and Randomized Trials Do, and Don't, Tell Us
When pregnancy complications threaten preterm delivery, clinicians routinely counsel expectant mothers about the use of steroids, medications that accelerate fetal lung maturation and reduce ...
In Conversation With… Marc Judson, MD
“If the issue were just to treat sarcoidosis, I would put everyone on 40 milligrams of prednisone, and every granuloma would be destroyed. But I'm not treating sarcoidosis disease. I'm treating the ...
Pulmonary Sarcoidosis Trial Flips the Playbook
A multicenter Dutch randomized trial published in the New England Journal of Medicine has shown that methotrexate can be used to replace prednisone as first-line therapy for symptomatic pulmonary ...
In Conversation With… Naomi Patel, MD MPH
“In just six months, more than 10% of patients on even moderate steroid regimens can develop new-onset diabetes.” Naomi Patel, MD MPH, a rheumatologist at Massachusetts General Hospital, is at the ...
Want a Steroid-Sparing Claim on Your Label? Start Here
Chronic glucocorticoid exposure, even at low doses, is now seen by regulators and clinicians as an unacceptable safety burden. Sponsors that prioritize steroid-toxicity from the outset position ...
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