The cost
of steroid-toxicity
is too high to be ignored

The true costs of steroid-toxicity have yet to be quantified


From cataracts to cardiovascular complications, the adverse events associated with long-term use of glucocorticoids are wide-ranging, taking a heavy toll on patients and healthcare systems.
Quantifying the economic impact of glucocorticoid-use is a key undertaking to enable value-based care for the millions of patients who suffer from inflammatory conditions, autoimmune diseases and cancer.

Metrics are essential in HEOR studies


Health economics outcomes research (HEOR) can help drug developers and healthcare decision-makers gain a better picture of how glucocorticoids and their myriad toxicities influence the value, cost and cost-effectiveness of available treatments. 


The STOX® Suite provides HEOR teams with scientifically rigorous assessments that reveal steroid-toxicity in prospective and retrospective studies of large patient populations.


The STOX Suite enables accurate measurement of steroid-toxicity. The STOX Suite includes clinical outcome assessments (COA) optimized for different settings:

  • The GTI: calculates change scores across nine health domains in adults
  • The GTI-MD: quantifies change across four metabolic domains in claims and EMR data
  • The pGTI: captures the change scores in nine health domains in children 


Bring hidden insights to light with GTI-MD

The Steritas GTI-MD is of particular utility for HEOR, enabling researchers to analyze large claims and electronic health record datasets to understand how glucocorticoid use and cumulative dose are associated with increased steroid-toxicity. This provides a foundation for assessing the benefits of non-steroid alternative treatments.


Through quantitative analysis of treatment costs associated with the 80+ known steroid-toxicities, researchers can use GTI-MD for retrospective data analysis to develop a more accurate picture of how glucocorticoids affect patients outside of controlled clinical trials and anecdotal data collected at the point of care.


Ultimately, these insights may inform treatment guidelines, payer coverage and help pharmaceutical companies make data-driven decisions about where the greatest medical needs lie when considering the development of new steroid-sparing therapies.

Is your HEOR team ready to do more with claims data?

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