Reconsidering Steroids: Origins, Paradox, and the Modern Standard of Care
On September 4, 1948, a bed-ridden 24-year-old woman with rheumatoid arthritis received the first dose of a glucocorticoid. The next morning she could walk. Twenty-three days later, her physicians ...
Mind the Measurement Gap
How health economics and outcomes research (HEOR) puts a value on steroid-toxicity A microsimulation model presented at ISPOR Europe 2025 put a number on the lifetime clinical and economic burden of ...
In Conversation With… Peter J. Neumann, ScD
"Nothing in healthcare saves money. It is not quite true, but it is a good adage to keep in mind." Health economics has spent four decades asking whether the trillions spent on US healthcare are ...
The Lifetime Cost of Long-Term Steroids
A microsimulation model has quantified what clinicians have long suspected: sustained steroid exposure in autoimmune disease carries a measurable, and avoidable, clinical and economic burden that ...
The HEOR Measurement Gap Pharma Can No Longer Ignore
Pharmaceutical companies need to replace dose reduction measures with direct toxicity measurement in health-economic models Dose reduction overlooks the hidden healthcare costs of steroid-toxicity. ...
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